Identification
and validation
of new therapeutic
targets



Helios Biosciences - Target Designer

Our R&D Program
Prostate Cancer
Immuno-dyn

Company Presentation (PDF)
WhitePaper (PDF)

European Projects
Valapodyn (Website, Brochure)
Tempo (Website)
Inflacare (Website)

Contact Us

Helios BioSciences
102, avenue Gaston Roussel
93230 Romainville
France
Phone : +33 (0)157 148 396
Fax : +33 (0)972 314 803
Contact



Helios BioSciences' know-how and 30 years expertise have enabled our company to optimize mRNA and protein expression analyses, using fast and cost-efficient techniques.
 
Helios BioSciences caters from experimental scheme design to result interpretation and ready-to-publish pictures





Tissue and Cell Expression

Helios BioSciences provides you with its Tissue and Cell Expression (TCE) technological platform. Our platform relies on robust techniques in :
  • In Situ Hybridisation (ISH)
  • ImmunoHistoChemistry (IHC)

to study mRNA and protein expressions on tissue sections.

TCE is best used just after the results of DNA microarrays. TCE makes it then possible to determine where these mRNAs are expressed and to relatively quantify their expressions.



TCE is therefore an attractive option to rt-PCR and can be used as a first choice following the DNA microarray results.


In Situ Hybridisation (ISH)
Helios BioSciences offers you different investigation strategies depending on your questions and on the abundance of the mRNA to be detected. Our expertise focuses on :

The making of probes and their labelling
Non radioactive labelling : riboprobes (fast qualitative analysis)
Radioactive labelling : oligonucleotides (easier to produce, they make the quantitative analysis possible)
Analysis at cellular and / or at tissular levels
Helios BioSciences analyses the images obtained and provides you with a detailed report the results


ImmunoHistoChemistry (IHC)
IHC analysis is based on a recognized platform composed of the whole equipment being required to run routine histological and immunohistochemical techniques.
 










Examples Of Services
And Final Results

Identification of the expression of a given mRNA at tissue and cell levels.

Quantitative analysis of the expression of given mRNAs.

mRNA expression in the neuromuscular junction.

Identification of mRNA and protein in the same cell on tissue sections.

Quantitative analysis of mRNA and protein expression.

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