Identification
and validation
of new therapeutic
targets



Helios Biosciences - Target Designer

Our R&D Program
Prostate Cancer
Epilepsy
Immuno-dyn

Contact Us

Helios BioSciences
8, avenue du Général Sarrail
94010 Créteil Cedex
France
Phone : +33 1 49 81 36 77
Contact

Company Profile (PDF)

WhitePaper (PDF)

Valapodyn (PDF)

Tempo (URL)




Primarily focused on cancer, neuronal degeneration and epilepsy, Helios Biosciences is your partner to help you to streamline your Drug Discovery process thanks to a unique technology integrating the dynamic dimension of biological processes. Helios develops a variety of offers to help the identification and characterization of therapeutic targets and biomarkers:

SIMPATHWAY (Smart Integrated Molecular Pathway) is a curated, directed and annotated molecular interaction network of intracellular signal transduction, delivered as a database that also includes query and data representation software.

PROPAGAPATH (Signal Propagation Analysis in Pathways) reveals the main molecular pathways involved in the physio-pathological processes of interest.

DYNAPATH: Helios Biosciences offers a new paradigm in systems biology: by introducing the dynamic dimension in the study of biological regulatory pathways, accurate therapeutic targets are characterized.


Take an analogy with car traffic. SIMPATHWAY would be a geographic map linking cities, PROPAGAPATH would highlight the most used roads during specific events, DYNAPATH would dynamically analyse the consequences of accidents (pathology) or aid services (cures) on the traffic.


Tissue & cell expression: Helios BioSciences' know-how and 20 years of expertise have enabled our company to optimize mRNA and protein expression analyses, using fast and cost-efficient techniques. Helios BioSciences caters from experimental scheme design to result interpretation and ready-to-publish pictures.

September 2007

18th : Our technology is presented during the « Transversales Santé ». More information and reservation here (French language is used for documents and conferences)

19th-21th Meet us on the French Pavillion in Yokohama (Japan) during BioJapan 2007

26th-28th: Pursuing the relationships with INRIA, Helios BioSciences together with major french Bio-IT companies will share a booth during Eurobio 2007 in Lille.

June 2007

5-7 th : Meet us in Tel-Aviv (Israel) during BioMed 2007 on the French Pavilion.

26th-28th Meet us in Paris (France) during Euro-Biotech Forum

May 2007

Helios BioSciences is the emerging company presented in the issue 355 of Biotech-Info

7th-10th: Meet us on the French Pavillion during Bio2007 in Boston (USA)

22th-25th: Meet us on our booth during the 8th Conference of the Société des Neurosciences in Montpellier.

March 2007

Helios Technology is presented in Biofutur. Download the translation in English

12th-14th:Meet us during BioSquare in Lyon (France)

January 2007

31th : Helios BioSciences closes a A financing round.

October 2006

19th-20th Helios BioSciences attend the Paris-Val de Marne Technology and Business Convention: MeetInnov 2006.

25th-26th Associated with INRIA and 3 French Bio-IT companies, Helios will expose its technology and offer at Eurobio 2006 in Paris.

27 th: Quick-off meeting of VALAPODYN hosted by Helios BioSciences in Paris.

September 2006

13 th-15th : Helios BioSciences attend Bio-Japan 2006 in Osaka (Japan)

June 2006

Second version of Immuno-dyn large-scale dynamic model of human T-lymphocyte intracellular signal transduction that drives the T-lymphocyte response to antigenic stimuli.

May 2006

16th : Meet us during the "Transversales Santé de Paris Technopole" (Helios Biosciences is a Biotech sponsor of the event).

April 2006

9-13th: Join us during the partnering meetings of Bio 2006 in Chicago (USA) or meet us at our booth in the France Pavilion (Région Ile de France).

11th : Meet us during the "Transversales Santé de Paris Technopole" (Helios Biosciences is a Biotech sponsor of the event).

March 2006

8-10th: Join us during the partnering meetings of BioSquare 2006 in Geneva (Switzerland).

14th : Meet us during the "Transversales Santé de Paris Technopole" (Helios Biosciences is a Biotech sponsor of the event).

14th: Presentation of our technology of Dynamic Modelling and Immunodyn at Gosau (Austria). 2nd FEBS Advanced Lecture Course on Systems Biology FEBS-sysBio2007: From Molecules to Life

February 2006

21th: Helios Biosciences will present its technology and offer during: Molecular Medicine Tri-Conference.

November 2005

7-9 th: Join us during the partnering meeting of Bio-Europe 2005, the 11th annual international partnering conference in Dresde (Germany).

29-30 th: Helios Biosciences will participate in the 9th European Biotech Crossroads in Lille (France), meet us on our booth (B14 espace Ile de france Agence Régionale de Développement) or during the partnering meetings.

August-September 2005

Helios Biosciences presents the scientific strategy of its drug targeting program for temporal lobe epilepsy during the 26th International Epilepsy Congress in Paris (France)..

August 2005

Publication of results of the collaboration between INSERM U513 and Helios Biosciences in Neuropharmacology (August 16, PMID: 16111724). Helios has carried out the in situ hybridisation experiments.

July 2005

Helios Biosciences presents new developments in its dynamic system biology approach applied to drug targeting, at the European Conference on Mathematical and Theoretical Biology 2005 in Dresde (Germany).

June 2005:

Helios Biosciences finalises the first large-scale dynamic model of human T-lymphocyte intracellular signal transduction that drives the T-lymphocyte response to antigenic stimuli. This model predicts relevant drug targets to act on the immune response and fully validates our scientific / technological approach.

Helios Biosciences participates to BIO 2005 (Philadelphia).

May 2005

Helios and INSERM sign a scientific collaboration agreement to characterize therapeutic targets to cure prostate cancer.

April 2005

Helios Biosciences and Neuromic sign a technical and commercial collaboration agreement in the area of gene expression analysis.

March 2005

Helios Biosciences presents its first dynamic model of the yeast fermentation / respiration intracellular molecular interaction network, during the SysBio 2005 international meeting in Gosau (Austria).


Testimonies
I warmly recommend resorting to Helios BioSciences for any operation of mRNA detection in the brain as well as in other tissues. Their professionalism, their know-how, their dynamism, their customer care and adaptability make them now indispensable collaborators."

Bruno Giros, PhD, Director of the INSERM Research Department U-513, "Neurobiology and Psychiatry"

The primary roadblock in exploring neuromuscular junctions is their relatively small size (~50nm). Helios has certainly shown that it is capable of overcoming barriers and exploring new grounds in science through dedication and persistence."

Javad Nazarian, M.S., The Children's National Medical Center, Washington DC.

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